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Is it time to delay second doses of coronavirus vaccines?

February 19, 2021. Summarized by summa-bot.

Compression ratio: 16.7%. 1 min read.

ROBBINSDALE, MN - DECEMBER 15: Systems Director Paul Krogh opens a box containing Pfizer-BioNTech COVID-19 vaccine doses at North Memorial Hospital on December 15, 2020 in Robbinsdale, Minnesota. Staff at the hospital are expected to start receiving the vaccine early next week. (Photo by Stephen Maturen/Getty Images)

Is it ok to delay or skip the secod dose of Covid-19 coronavirus vaccine to strecth out supply?

(CNN)Two letters to major medical journals this week provide fuel for the argument that in these times of scarce coronavirus vaccine, people can skip their second doses, immediately doubling the supply for others.

In between their first and second doses of the Pfizer/BioNTech vaccine, rates of infected plummeted.

In a second, Canadian researchers found evidence of more than 90% protection after a single dose of the Pfizer/BioNTech vaccine.

Dr. Tom Frieden, a former director of the US Centers for Disease Control and Prevention who is now CEO of the health advocacy organization Resolve to Save Lives, says there are arguments for and against delaying the second dose until millions of people can be vaccinated.

In addition, for mRNA vaccines such as the Pfizer and Modena vaccines, it is not yet known whether the timing of the second dose is critical to producing a sustained immune response, because mRNA vaccines had not been used in late-stage trials or approved for use prior to the COVID-19 pandemic," Frieden noted.

"It is not clear how well a single dose of any two-dose COVID-19 vaccine may prevent infection with emerging variants," Frieden noted.

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