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How J&J's coronavirus vaccine is different from the others

February 27, 2021. Summarized by summa-bot.

Compression ratio: 18.9%. 1 min read.

The United States is poised to get a third coronavirus vaccine -- this one made by Johnson & Johnson.

But the FDA authorization says two doses, and many vaccine experts, including White House chief medical adviser Dr. Anthony Fauci, fear giving just one dose of Pfizer and Moderna's vaccines might leave people only partly protected.

Johnson & Johnson's vaccine was tested and shown to protect people with a single dose, although studies are underway to see if two doses might provide more protection.

One thing people might notice right away about the Johnson & Johnson vaccine is how it stacks up against Pfizer's and Moderna's in terms of efficacy.

It was tested in 44,000 people in the US, South Africa and Latin America, and most of the testing was months later in the pandemic than the Pfizer and Moderna vaccines, which started testing in the spring and summer.

With the Johnson & Johnson vaccine, protection against moderate to severe disease starts about two weeks after people get vaccinated.

Recent studies show good level of protection with the first dose of the Moderna and Pfizer vaccines, but people don't get full protection until about two weeks after the second dose -- so five to six weeks after the first dose.

Like the Pfizer and Moderna vaccines, it delivers genetic instructions.

The CDC reports only a few cases of anaphylaxis in people who have been given the Moderna or Pfizer vaccines, and all were easily treated.

Only one case of anaphylaxis has been reported in the 44,000 people who have tested the Johnson & Johnson vaccine.

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