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Concerns grow as Chinese Covid-19 vaccine far less effective than initially claimed in Brazil

January 13, 2021. Summarized by summa-bot.

Compression ratio: 24.4%. 1 min read.

A leading Chinese Covid-19 vaccine developed by Sinovac Biotech was just 50.38% effective in late-stage trials in Brazil, significantly lower than earlier results showed, according to a statement published by the government of Sao Paulo Tuesday.

(CNN)A leading Chinese Covid-19 vaccine developed by Sinovac Biotech was just 50. 38% effective in late-stage trials in Brazil, significantly lower than earlier results showed, according to a statement published by the government of Sao Paulo Tuesday.

Analysts said the efficacy rate of Sinovac's Coronavac vaccine in Brazil -- the lowest among its global competitors -- could affect international confidence in Chinese-made vaccines and hamper Beijing's effort to repair its image from its early mishandling of the initial outbreak by providing Covid-19 vaccines to developing countries.

Despite the worse than anticipated results, Huang said the Sinovac vaccine would still be "usable" by helping to relieve pressures on healthcare systems while reducing potential deaths, given its higher efficacy for moderate and severe cases that would require medical treatment.

Sinovac's vaccine has had wildly different results from three countries: Indonesian drug regulators say interim data from Phase 3 trials showed it is 65. 3% effective and gave it the country's first emergency use approval; Turkey says it is 91. 25% effective; And in Brazil, the two significantly different efficacy rates announced a week apart have further sparked questions.

Last week, Brazil's health regulator agency ANVISA told the Butantan Institute that in order to approve the emergency use of a vaccine, the global efficacy rate had to be made publicly available -- information the Institute had not received at the time from Sinovac, according to CNN Brasil sources.

"If people learn about this, they might start to question the safety and efficacy of the Sinovac vaccine, or even other Chinese-made vaccines," Huang said.

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